Prof. Dr. med. Joachim Wölfle

Publikationsverzeichnis PD Dr. med. André Hörning

A.       Originalarbeiten

1.    Tebbe B, Wilde B, Wang J, Wang X, Jian F, Dolff S, Schedlowski M, Kribben A, Witzke O and Hoerning  A.  Renal  Transplant  Recipients  lack  circulating  immature  CD19+CD24hiCD38hi Interleukin-10 producing Regulatory B-Lymphocytes, PLOSone 5. April 2016.

2.  Heinemann K, Wilde B, Hoerning A, Tebbe B, Kribben A, Witzke O, Dolff S (2016) Decreased IL-10± regulatory B cells (Bregs) in lupus nephritis patients. Scand J Rheumatol 2016 Mar 7:1-5.

3.    Hoerning A, Wilde B, Wang J, Tebbe B, Jing L, Wang X, Jian F, Dolff S, Kribben A, Hoyer PF and Witzke  O.  Pharmacodynamic   monitoring  of  mTOR  inhibition  by  phosphoflow  cytometric determination of p70S6 kinase activity, Transplantation, 2015 Jan; 99(1):210-9.

4.    Wilde B, Hoerning A, Kribben A, Witzke O, Dolff S. (2013) Signal Tranducers and Activators of Transcription  (STAT):  Expression  and  Function  in  ANCA-associated  vasculitis.  Mol  Med  Rep. 2014 Jun;9(6):2316-20. doi: 10.3892/mmr.2014.2062

5.   Wilde  B,  Hoerning  A,  Kribben  A,  Witzke  O,  Dolff  S.  Abnormal  expression  pattern  of  the   IL-2 receptor  ß-chain  on  CD4+  T-cells  in  ANCA-associated  vasculitis.  Disease  Markers   2014:249846. doi: 10.1155/2014/249846

6.    Hoerning  A, Raub S, Kathemann  S, Stehling F, Müntjes C, Neudorf U, Hoyer PF, Gerner P. Pulse Oximetry is insufficient for timely Diagnosis of Hepatopulmonary Syndrome in Children with Liver Cirrhosis, Journal of Pediatrics 2014; 164(3):546-552.

7.   Hoerning  A,  Hegen  B,  Wingen  AM,  Cetiner  M,  Lainka  E,  Fiedler  M,  Timm  J,  Wenzel J, Kathemann S, Hoyer PF, Gerner P. Prevalence of Hepatitis E Virus Infection in Pediatric Solid  Organ Transplant Recipients – a Single Center Experience, Pediatric Transplantation 2012, Nov;16(7):742-7.

8.  Hoerning A, Köhler S, Jun C, Jian F, Hua F, Wilde B, Feldkamp T, Briscoe DM, Kribben A, Hoyer PF, Witzke O. Peripherally Circulating CXCR3+FOXP3+  and CCR5+FOXP3+  Tregs Correlate with Stable Renal Allograft Function. Scand J Immunol. 2012 Sep;76(3):320-8.

9.  Hoerning  A, Köhler S, Jun C, Jian F, Tebbe B, Feldkamp  T, Kribben A, Hoyer PF, Witzke O. Cyclosporine A but not Everolimus Affects Expression of Chemokine Receptors on CD4+  T cell subsets. Clin Exp Immunol. 2012 May;168(2):251-9.

10. Gerner  P,  Hörning  A,  Kathemann  S,  Willuweit  K  and  Wirth  S.  Growth  abnormalities  in children with chronic hepatitis B or C. Adv Virol. 2012: 670316. Epub 2012 Mar 4th.

11. Hoerning  A, Kalkavan H, Rehme C, Menke J, Worm K, Garritsen HSP, Büscher R, Hoyer PF. Quantitative Real-Time ARMS-qPCR for mitochondrial DNA enables accurate detection of microchimerism in renal transplant recipients. Pediatric Transplantation 2011; 15(8):809-818.

12. Hoerning  A, Koss  K, Datta  D, Boneschansker  L, Jones  CN, Wong  IY, Irimia  D, Calzadilla  K, Benitez  F, Hoyer  PF,  Harmon  WE,  Briscoe  DM.  Subsets  of human  CD4+   T regulatory  cells express  the  peripheral  homing  receptor  CXCR3.  European  Journal  of  Immunology,  2011, 41(8):2291-302.

13. Basu  A*,  Hoerning  A*,  Datta  D, Edelbauer  M,  Stack  MP,  Calzadilla  K, Pal  S, Briscoe  DM. Cutting  Edge:  Vascular  Endothelial  Growth  Factor-Mediated  Signaling  in  Human  CD45RO+ CD4+    T  Cells  Promotes   Akt  and  ERK  Activation   and  Costimulates   IFN-g Production.   J. Immunology 2010 Jan 15; 184(2): 545-549. * Shared first authorship.

14. Schatton T, Schuette U, Frank NY, Zhan Q, Hoerning A, Robles SC, Zhou J, Hodi FS, Spagnoli GC, Murphy GF, Frank MH. Modulation of T Cell Activation by Malignant Melanoma Initiating Cells. Cancer Research 2010, 15; 70(2): 697-708.

15. Contreras AG, Dormond O, Edelbauer M, Calzadilla K, Hoerning A, Pal S, Briscoe DM. mTOR- understanding the clinical effects. Transplant Proc. 2008 Dec; 40(10 Suppl.): S9-S12.

16. Becker JU, Hoerning A, Schmid KW, Hoyer PF (2007) Immigrating progenitor cells contribute to human podocyte turnover, Kidney Int. 2007; 72(12):1468-73.

17. Büscher R, Hoerning  A, Patel HH, Zhang S, Arthur DB, Grasemann H, Ratjen F and Insel PA (2006)  P2Y2  receptor  polymorphisms  and haplotypes  in cystic  fibrosis and their impact  on Ca2+ influx, Pharmacogenetics and Genomics 2006; 16(3):199-205.

18. Warner JB, Bruin EJ, Hannig H, Hellenkamp F, Hörning A, Mittmann K, van der Steege GJ, de Leij LF and Garritsen HS (2006) Use of sequence variation in three highly variable regions of the  mitochondrial  DNA  for  the  discrimination  of  allogeneic  platelets,  Transfusion  2006; 46(4):554-561.

19. Tang CM, Hoerning A, Büscher R, O`Connor DT, Ratjen F, Grasemann H and Insel PA (2005) Human adenosine 2B receptor: SNP discovery and evaluation of expression in patients with cystic fibrosis, Pharmacogenetics and Genomics 2005; 15:321-327.

20. Hutter  G, Nickenig  C, Garritsen  H, Hellenkamp  F, Hoerning  A, Hiddemann  W, Dreyling  M (2004) Use of polymorphisms  in the noncoding region of the human mitochondrial  genome to  identify  potential  contamination  of  human  leukemia-lymphoma   cell  lines.  Hematol  J. 2004; 5(1):61-8.

21. Garritsen HSP, Hoerning A, Hellenkamp F, Cassens U, Mittmann K and Sibrowski W (2001) Polymorphisms in the non-coding region of the human mitochondrial genome in unrelated plateletapheresis donors, British Journal of Haematology 2001, 112 (4): 995-1003.

22. Garritsen HS, Hellenkamp F, Hoerning A, Mittmann K and Sibrowski W (2001) Identifying allogeneic  platelets  by  resolution  of  point  mutations  in  mitochondrial  DNA  using  single- stranded conformational polymorphism PCR, Transfusion 2001; 41(12): 1531-1538.


B.         Fallmitteilungen

1.  Jabari S, Carbon R, Besendörfer M, Hartmann A, Rompel O, Hoerning A, Söder S. Asymmetric Omphalophagus in a Triplet after in vitro fertilization: A rare case of conjoined twinning, Case Rep. Pediatrics 2018, 2018:9349606. doi: 10.1155/2018/9349606.

2.  Rechenauer T, Raithel R, Götze T, Siebenlist G, Rückel A, Baenkler HW, Hartmann A, Haller F and Hoerning A Idiopathic mast cell activation syndrome (IMCAS) with associated salicylate intolerance,  Frontiers in Pediatrics,  Case Report, 2018

3.   Multi-Step treatment of ultra-short bowel syndrome with unclear outcome in a newborn with prenatal known gastroschisis. Müller-Kühnle JC, Busch J, Hoerning A, Berclaz LM, Bodenschatz KJ, EC Pediatrics, 2018             

4.   Jabari S, Soeder S, Besendoerfer  M, Carbon R, Hartmann  A, Doll U, Hoerning  A Congenital Esophageal  Stenosis  due  to  tracheobronchial  remnants:  a  case  report,  SAJ  Case  Reports 2017, ISSN:2375-7043.


C.         Übersichtsarbeiten in Zeitschriften

1.    Hoerning   A.  p70S6-Kinase   -  Ein  Indikator   zur  pharmakodynamischen   Einschätzung   der klinischen Effizienz einer mTOR-Inhibitor-basierten Immunsuppression? Invited Review, Der Nephrologe, September 2015, Volume 10, Issue 5, pp 423-426

2.  Götze T, Blessing H, Grillhösl C, Gerner P, Hoerning A. Neonatal Cholestasis – differential diagnoses, current diagnostic procedures and treatment, Review, Frontiers in Pediatrics Jun 17;3:43. doi: 10.3389/fped.2015.00043. 2015.

3.   Hoerning  A, Wilde B. FoxP3 - Stabilitäts-  und Expressionspotenzierung  durch epigenetische Regulation, invited Review, Der Nephrologe 2012, Nov; 7(6):508-510

4. Contreras AG, Dormond O, Edelbauer M, Calzadilla K, Hoerning A, Pal S, Briscoe DM mTOR– Understanding the clinical effects, Transplantation Proceedings, Vol40, Issue 10, pp9-12.


D.        Buchbeiträge

1.     Mastzellbeteiligung bei chronischen Bauchschmerzen im Kindesalter, in Salicylatintoleranz von H.W. Baenkler, pp55-62, Dustri Verlag 2019, ISBN: 978-3-87185-525-2


E.         Vorträge

a.   Wissenschaftliche  Vorträge:  10 zur translationalen  Transplantforschung,  3 zum hepatopulmonalen Syndrom im Kindesalter, 5 zur eosinophilen Ösophagitis im Kindesalter

b.    Zahlreiche Fortbildungsvorträge: >80


Erlangen, den 10.06.2019

PD Dr. med. André Hörning