2011

Publikationen
2011

Originalpublikationen aus der Kinder- und Jugendklinik:

Hammersen J, Neukam V, Nüsken KD, Schneider H (2011) Systematic evaluation of exertional hyperthermia in children with hypohidrotic ectodermal dysplasia: an observational study. Pediatr. Res. 70: 297-301

Gelse K, Schneider H (2011) In vivo evaluation of gene transfer into mesenchymal cells. Methods Mol. Biol. 737: 391-405

Pacho F, Zambruno G, Calabresi V, Kiritsi D, Schneider H (2011) Efficiency of translation termination in humans is highly dependent upon nucleotides in the neighborhood of a (premature) termination codon. J. Med. Genet. 48: 640-644

Kuster L, Grausenburger R, Fuka G, Kaindl U, Krapf G, Inthal A, Mann G, Kauer M, Rainer J, Kofler R, Hall A, Metzler M, Meyer LH, Meyer C, Harbott J, Marschalek R, Strehl S, Haas OA, Panzer-Grümayer R (2011) ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling. Blood 117: 2658-2667

Edelbauer M, Kshirsagar S, Riedl M, Haffner D, Billing H, Tönshoff B, Ross S, Dötsch J, Amon O, Fehrenbach H, Steuber C, Beissert A, Hager J, Wechselberger G, Weber LT, Zimmerhackl LB (2011) Markers of childhood lupus nephritis indicating disease activity. Pediatr. Nephrol. 26: 401–410

Fujiwara H, Ferreira M, Donati G, Marciano DK, Linton JM, Sato Y, Hartner A, Sekiguchi K, Reichardt LF, Watt FM (2011) The basement membrane of hair follicle stem cells is a muscle cell niche. Cell 144:577-89

Nüsken KD, Schneider H, Plank C, Trollmann R, Nüsken E, Rascher W, Dötsch J (2011) Fetal Programming of Gene Expression in Growth-Restricted Rats Depends on the Cause of Low Birth Weight. Endocrinology 152: 1327-1335

Schneider H, Hammersen J, Preisler-Adams S, Huttner K, Rascher W, Bohring A (2011) Sweating ability and genotype in individuals with X-linked hypohidrotic ectodermal dysplasia. J. Med. Genet. 48: 426-432

Rettinger E, Willasch AM, Kreyenberg H, Borkhardt A, Holter W, Kremens B, Strahm B, Woessmann W, Mauz-Koerholz C, Gruhn B, Burdach S, Albert MH, Schlegel PG, Klingebiel T, Bader P (2011) Preemptive immunotherapy in childhood acute myeloid leukemia for patients showing evidence of mixed chimerism after allogeneic stem cell transplantation. Blood 118: 5681-5688

Amann K, Odoni G, Benz K, Campean V, Jacobi J, Hilgers KF, Hartner A, Veelken R, Orth SR (2011) Sympathetic blockade prevents the decrease in cardiac VEGF expression and capillary supply in experimental renal failure. Am. J. Physiol. Renal Physiol. 300: F105-112

Kraft M, Cirstea IC, Voss AK, Thomas T, Goehring I, Sheikh BN, Gordon L, Scott H, Smyth GK, Ahmadian MR, Trautmann U, Zenker M, Tartaglia M, Ekici A, Reis A, Dörr HG, Rauch A, Thiel CT (2011) Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome-like phenotype and hyperactivated MAPK signaling in humans and mice. J. Clin. Invest. 121: 3479-3491

Neubert A, Hsia Y, de Jong-van den Berg LT, Janhsen K, Glaeske G, Furu K, Kieler H, Nørgaard M, Clavenna A, Wong IC (2011) Comparison of anti-diabetic drug prescribing in children and adolescents in seven European countries. Br. J. Clin. Pharmacol. 72: 969-977

Raue F, Pichl J, Dörr HG, Schnabel D, Heidemann P, Hammersen G, Jaursch-Hancke C, Santen R, Schöfl C, Wabitsch M, Haag C, Schulze E, Frank-Raue K (2011) Activating mutations in the calcium-sensing receptor: genetic and clinical spectrum in 25 patients with autosomal dominant hypocalcaemia - a German survey. Clin. Endocrinol (Oxf) 75: 760-765

Benz K, Campean V, Cordasic N, Karpe B, Neuhuber W, Mall G, Hartner A, Hilgers KF, Amann K (2011) Early glomerular alterations in genetically determined low nephron number. Am. J. Physiol. Renal Physiol. 300: F521-530

Benz K, Amann K (2011) Endothelin in diabetic renal disease. Contrib. Nephrol. 172: 139-148

Tzschoppe A, Struwe E, Rascher W, Dörr HG, Schild RL, Goecke TW, Beckmann MW, Hofner B, Kratzsch J, Dötsch J (2011) Intrauterine growth restriction (IUGR) is associated with increased leptin synthesis and binding capability in neonates. Clin Endocrinol (Oxf) 74: 459-466

Bien E, Godzinski J, Dall'igna P, Defachelles AS, Stachowicz-Stencel T, Orbach D, Bisogno G, Cecchetto G, Warmann S, Ellerkamp V, Brennan B, Balcerska A, Rapala M, Brecht I, Schneider D, Ferrari A (2011) Pancreatoblastoma: a report from the European cooperative study group for paediatric rare tumours (EXPeRT). Eur. J. Cancer 47: 2347-2352

Völkl TM, Ohl L, Rauh M, Schöfl C, Dörr HG (2011) Adrenarche and puberty in children with classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Horm. Res. Paediatr. 76: 400-410

Zahnleiter D, Trautmann U, Ekici AB, Goehring I, Reis A, Dörr HG, Rauch A, Thiel CT (2011) Familial short stature due to a 5q22.1-q23.2 duplication refines the 5q duplication spectrum. Eur. J. Med. Genet. 54: e521-524

Tzschoppe A, Fahlbusch F, Seidel J, Dörr HG, Rascher W, Goecke TW, Beckmann MW, Schild RL, Struwe E, Dötsch J (2011) Dexamethasone stimulates the expression of leptin and 11?-HSD2 in primary human placental trophoblastic cells. Eur. J. Obstet. Gynecol. Reprod. Biol. 156: 50-55

Reinehr T, Bechtold-Dalla Pozza S, Bettendorf M, Dörr HG, Gohlke B, Hauffa BP, Kaspers S, Land C, Mehls O, Schwab KO, Stahnke N, Ranke MB, German KIGS Study Board (2011) Impact of overweight on effectiveness of treatment with human growth hormone in growth hormone deficient children: analysis of German KIGS data. Exp. Clin. Endocrinol. Diabetes 119: 544-548

Völkl TM, Rauh M, Schöfl C, Dörr HG (2011) IGF-I-IGFBP-3-acid-labile subunit (ALS) complex in children and adolescents with classical congenital adrenal hyperplasia due to 21-hydroxylase deficiency (CAH). Growth Horm. IGF Res. 21: 191-198

Rodeberg DA, Anderson JR, Arndt CA, Ferrer FA, Raney RB, Jenney ME, Brecht IB, Koscielniak E, Carli M, Bisogno G, Oberlin O, Rey A, Ullrich F, Stevens MC, Meyer WH (2011) Comparison of outcomes based on treatment algorithms for rhabdomyosarcoma of the bladder/prostate: combined results from the Children's Oncology Group, German Cooperative Soft Tissue Sarcoma Study, Italian Cooperative Group, and International Society of Pediatric Oncology Malignant Mesenchymal Tumors Committee. Int. J. Cancer 128: 1232-1239

Bauer S, Park J, Pittrof A, Song YY, von der Mark K, Schmuki P (2011) Covalent functionalization of TiO2 nanotube arrays with EGF and BMP-2 for modified behaviour towards mesenchymal stem cells. Integr. Biol. 3: 927-936

Lell MM, May M, Deak P, Alibek S, Kuefner M, Kuettner A, Köhler H, Achenbach S, Uder M, Radkow T (2011) High-pitch spiral computed tomography: effect on image quality and radiation dose in pediatric chest computed tomography. Invest. Radiol. 46: 116-123

Heeringa SF, Chernin G, Chaki M, Zhou W, Sloan AJ, Ji Z, Xie LX, Salviati L, Hurd TW, Vega-Warner V, Killen PD, Raphael Y, Ashraf S, Ovunc B, Schoeb DS, McLaughlin HM, Airik R, Vlangos CN, Gbadegesin R, Hinkes B, Saisawat P, Trevisson E, Doimo M, Casarin A, Pertegato V, Giorgi G, Prokisch H, Rötig A, Nürnberg G, Becker C, Wang S, Ozaltin F, Topaloglu R, Bakkaloglu A, Bakkaloglu SA, Müller D, Beissert A, Mir S, Berdeli A, Varpizen S, Zenker M, Matejas V, Santos-Ocaña C, Navas P, Kusakabe T, Kispert A, Akman S, Soliman NA, Krick S, Mundel P, Reiser J, Nürnberg P, Clarke CF, Wiggins RC, Faul C, Hildebrandt F (2011) COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. J. Clin. Invest. 121: 2013-2024

Knier B, Cordasic N, Klanke B, Heusinger-Ribeiro J, Daniel C, Veelken R, Hartner A, Hilgers KF (2011) Effect of the plasminogen-plasmin system on hypertensive renal and cardiac damage. J. Hypertens. 29: 1602-1612

Pilic D, Fröhlich T, Nöh F, Pappas A, Schmidt-Choudhury A, Köhler H, Skopnik H, Wenzl TG (2011) Detection of gastroesophageal reflux in children using combined multichannel intraluminal impedance and pH measurement: Data from the German Pediatric Impedance Group. J. Pediatr. 158: 650-654.e1

Koal T, Schmiederer D, Pham-Tuan H, Röhring C, Rauh M (2011) Standardized LC-MS/MS based steroid hormone profile-analysis. J. Steroid Biochem. Mol. Biol. 129: 129-138

Amann K, Benz K (2011) [Clinical relevance of reduced nephron count]. Klin. Pädiatr. 223: S18-26

Brecht IB, Schneider DT, Klöppel G, von Schweinitz D, Barthlen W, Hamre MR (2011) Malignant pancreatic tumors in children and young adults: evaluation of 228 patients identified through the Surveillance, Epidemiology, and End Result (SEER) database. Klin. Pädiatr. 223: 341-345

Nonnenmacher L, Langer T, Blessing H, Gabriel H, Buchwald HJ, Meneksedag C, Kohne E, Gencik M, Debatin KM, Cario H (2011) Hereditary hyperferritinemia cataract syndrome: clinical, genetic, and laboratory findings in 5 families. Klin. Pädiatr. 223: 346-351

Rascher W (2011) [Angiotensin II-receptor (type AT1)-antagonists and fetal impairment]. Klin. Pädiatr. 223: 4

Ritz E, Amann K, Koleganova N, Benz K (2011) Prenatal programming-effects on blood pressure and renal function. Nat. Rev. Nephrol. 7: 137-144

Tyralla K, Adamczak M, Benz K, Campean V, Gross ML, Hilgers KF, Ritz E, Amann K (2011) High-dose enalapril treatment reverses myocardial fibrosis in experimental uremic cardiomyopathy. PLoS One 6: e15287

Topf HG, Lischetzki G, Trollmann R, Rascher W, Rauh M (2011) The effect of valproate therapy on thrombin generation determined by calibrated automated thrombography. Klin. Pädiatr. 223: 165-168

Alejandre-Alcázar MA, Boehler E, Amann K, Klaffenbach D, Hartner A, Allabauer I, Wagner L, von Hörsten S, Plank C, Dötsch J (2011) Persistent changes within the intrinsic kidney-associated NPY system and tubular function by litter size reduction. Nephrol. Dial. Transplant. 26: 2453-2465

Amann K, Benz K (2011) Statins – beyond lipids in CKD. Nephrol. Dial. Transplant. 26: 407-410

Menendez-Castro C, Fahlbusch F, Cordasic N, Amann K, Münzel K, Plank C, Wachtveitl R, Rascher W, Hilgers KF, Hartner A (2011) Early and late postnatal myocardial and vascular changes in a protein restriction rat model of intrauterine growth restriction. PLoS One 6: e20369

Amann K, Büttner M, Benz K, Schöcklmann H (2011) [Kidney transplant pathology]. Pathologe 32: 124-134

von Hoff K, Hinkes B, Dannenmann-Stern E, von Bueren AO, Warmuth-Metz M, Soerensen N, Emser A, Zwiener I, Schlegel PG, Kuehl J, Frühwald MC, Kortmann RD, Pietsch T, Rutkowski S (2011) Frequency, risk-factors and survival of children with atypical teratoid rhabdoid tumors (AT/RT) of the CNS diagnosed between 1988 and 2004, and registered to the German HIT database. Pediatr. Blood Cancer 57: 978-985

Brackmann FA, Kiefer A, Agaimy A, Gencik M, Trollmann R (2011) Rapidly progressive phenotype of Lafora disease associated with a novel NHLRC1 mutation. Pediatr. Neurol. 44: 475-477

Klaffenbach D, Friedrich D, Strick R, Strissel PL, Beckmann MW, Rascher W, Gessner A, Dötsch J, Meissner U, Schnare M (2011) Contribution of different placental cells to the expression and stimulation of antimicrobial proteins (AMPs). Placenta 32: 830-837

Klaffenbach D, Meissner U, Raake M, Fahlbusch F, Alejandre Alcazar MA, Allabauer I, Kratzsch J, Rascher W, Dötsch J (2011) Upregulation of leptin-receptor in placental cells by hypoxia. Regul. Pept. 167: 156-162

Topf HG, Weiss D, Lischetzki G, Strasser E, Rascher W, Rauh M (2011) Evaluation of a modified thromboelastography assay for the screening of von Willebrand disease. Thromb. Haemost. 105: 1091-1099

Büttner M, Dittrich K, Schott GE, Uder M, Leuschner I, Dötsch J, Holter W, Amann K, Benz K (2011) Recurrent gross hematuria with positive family history of IgA nephropathy and an unexpected diagnosis. Urology 78: 427-430

Paulides M, Stöhr W, Laws HJ, Graf N, Lakomek M, Berthold F, Schmitt K, Niggli F, Jürgens H, Bielack S, Koscielniak E, Klingebiel T, Langer T (2011) Antibody levels against tetanus and diphtheria after polychemotherapy for childhood sarcoma: a report from the Late Effects Surveillance System. Vaccine 29: 1565-1568

Kreyenberg H, Jarisch A, Bayer C, Schuster B, Willasch A, Strahm B, Kremens B, Gruhn B, Schrauder A, Burdach S, Führer M, Rossig C, Kabisch H, Schlegel PG, Stachel D, Beck JF, Mauz-Koerholz C, Chung TL, Holler E, Klingebiel T, Bader P (2011) NOD2/CARD15 gene polymorphisms affect outcome in pediatric allogeneic stem cell transplantation. Blood 118: 1181-1184

Dörr HG, Bettendorf M, Hauffa BP, Mehls O, Rohrer T, Stahnke N, Pfäffle R, Ranke MB, German KIGS Group (2011) Different relationships between the first 2 years on growth hormone treatment and the d3-growth hormone receptor polymorphism in short small-for-gestational-age (SGA) children. Clin. Endocrinol. (Oxf) 75: 656-660

Zivicnjak M, Schnabel D, Staude H, Even G, Marx M, Beetz R, Holder M, Billing H, Fischer DC, Rabl W, Schumacher M, Hiort O, Haffner D, Hypophosphatemic Rickets Study Group of the Arbeitsgemeinschaft für Pädiatrische Endokrinologie and Gesellschaft für Pädiatrische Nephrologie (2011) Three-year growth hormone treatment in short children with X-linked hypophosphatemic rickets: effects on linear growth and body disproportion. J. Clin. Endocrinol. Metab. 96: e2097-2105

Ladenstein R, Pötschger U, Siabalis D, Garaventa A, Bergeron C, Lewis IJ, Stein J, Kohler J, Shaw PJ, Holter W, Pistoia V, Michon J (2011) Dose finding study for the use of subcutaneous recombinant interleukin-2 to augment natural killer cell numbers in an outpatient setting for stage 4 neuroblastoma after megatherapy and autologous stem-cell reinfusion. J. Clin. Oncol. 29: 441-448

Schöffl I, Schöffl V, Dötsch J, Dörr HG, Jüngert J (2011) Correlations between high level sport-climbing and the development of adolescents. Pediatr Exerc Sci. 23: 477-486